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Phentermine is a medication for chronic weight management. It is for people with overweight
and weight-related complications or obesity. It is meant to be used together with a lifestyle
therapy regimen involving a reduced calorie diet and increased physical activity.
How Does Phentermine Work?
Phentermine is an appetite suppressant that works in the brain.
Who Should Not Take Phentermine?
• People who have heart disease or uncontrolled hypertension
• Women who are pregnant, nursing, or planning to become pregnant
• People who have glaucoma
• People with uncontrolled hyperthyroidism (overactive thyroid)
• People who are taking a monoamine oxidase inhibitor (MAOI) now or have taken one
within the past 14 days
• People who are prone to agitation (extreme restlessness and irritability)
• People with a history of drug abuse

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Phentermine is used together with diet and exercise to treat Obesity.

How To Take

The usual dosage for Phentermine is 37.5 mg once per day or 15 mg once or twice per day. In order to
prevent sleep disturbances, it is best to take the medication in the early morning before breakfast or at least
10-14 hours before bedtime. If you miss a dose, take the medication as soon as you remember, but avoid
evening dosing. Do not take extra medicine to make up the missed dose.
After long-term use of Phentermine, you may have withdrawal effects including fatigue and depression if
you stop taking the medication suddenly. Please talk to your provider at SRMS before stopping this

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Side Effects

What Are the Common Side Effects of Phentermine?
• Dry mouth
• Restlessness
• Difficulty sleeping
• Increase in heart rate
• Increase in blood pressure

What Are the Possible Serious Side Effects of Phentermine?
Primary Pulmonary Hypertension
A rare but often fatal disease of the lungs known as primary pulmonary hypertension has
been reported in patients taking phentermine and phentermine-like products. Stop taking
phentermine and call your doctor if you experience any difficulty breathing, severe chest
pain, fainting, or swelling in the legs.
Heart Valve Disease
Serious heart valve problems or disease have been reported in patients taking phentermine
or other phentermine-like products for weight loss. The possibility of an association cannot
be ruled out.
Low Blood Sugar (Hypoglycemia)
Weight loss can cause low blood sugar in people with type 2 diabetes who also take
medicines used to treat type 2 diabetes. Test your blood sugar before and during treatment
with phentermine.

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Absolute Contraindications:
Do not take Phentermine if you have:
? Heart disease
? Atherosclerosis (hardening of the arteries)
? Uncontrolled High Blood Pressure
? Overactive Thyroid
? Glaucoma
? Are in an agitated state
? An Allergy to the medication
? Used a medication with the classification of MAO inhibitor in the past 14 days.
Do not take Phentermine with other diet medications such as Fenfluramine (Phen-Fen) or Dexfenfluramine
(Redux) as this combination can cause a rare fatal lung disorder called pulmonary hypertension.
Relative Contraindications:
It is recommended that you avoid alcoholic beverages while taking this medication because alcohol can
increase some of the side effects of Phentermine.

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